At its heart, the Scopes Trial was a clash between
a. biology and science. c. evolution and science.
b. education and science. d. religion and science. .

At its heart, the Scopes Trial was a clash between religion (creationism) and science (evolution). The Scopes Trial was an American legal case between the State of Tennessee and John Scopes, a high school teacher. 

1. 21st amendment 2. Religion and science. 3. They feared the loss of jobs and damage to Americans traditions 4. That america was a melting pot